Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model

Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model

5-fluorouracil or 5-FU (a chemotherapeutic medication) has been revealed to induce memory deficits in many cancer patients. Asiatic acid (AA) is a triterpenoid extract from Centella asiatica. This compound can ameliorate intracellular oxidative stress caused by chemotherapy drugs. Recent studies hav...

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Bibliographic Details
Main Authors: Jariya Umka Welbat, Pornthip Chaisawang, Wanassanun Pannangrong, Peter Wigmore
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Nutrients
Subjects:
5-fluorouracil
asiatic acid
neuroprotection
hippocampus
Online Access:http://www.mdpi.com/2072-6643/10/8/1053

Internet

http://www.mdpi.com/2072-6643/10/8/1053

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