Equol Pretreatment Protection of SH-SY5Y Cells against Aβ (25–35)-Induced Cytotoxicity and Cell-Cycle Reentry via Sustaining Estrogen Receptor Alpha Expression

β-amyloid formation in the brain is one of the characteristics of Alzheimer’s disease. Exposure to this peptide may result in reentry into the cell cycle leading to cell death. The phytoestrogen equol has similar biological effects as estrogen without the side effects. This study...

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Bibliographic Details
Main Authors: Meng-Chao Tsai, Shyh-Hsiang Lin, Kiswatul Hidayah, Ching-I Lin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/10/2356