Engineering of <em>Streptoalloteichus tenebrarius</em> 2444 for Sustainable Production of Tobramycin

Engineering of <em>Streptoalloteichus tenebrarius</em> 2444 for Sustainable Production of Tobramycin

Tobramycin is a broad-spectrum aminoglycoside antibiotic agent. The compound is obtained from the base-catalyzed hydrolysis of carbamoyltobramycin (CTB), which is naturally produced by the actinomycete <i>Streptoalloteichus tenebrarius</i>. However, the strain uses the same precursors to...

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Bibliographic Details
Main Authors: Lena Mitousis, Hannes Maier, Luka Martinovic, Andreas Kulik, Sigrid Stockert, Wolfgang Wohlleben, Alfred Stiefel, Ewa M. Musiol-Kroll
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
actinomycetes
antibiotic
aminoglycoside
carbamoyltobramycin
tobramycin
apramycin
Online Access:https://www.mdpi.com/1420-3049/26/14/4343

Internet

https://www.mdpi.com/1420-3049/26/14/4343

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