Enhanced Expression of <i>miR-181b</i> in B Cells of CLL Improves the Anti-Tumor Cytotoxic T Cell Response

Enhanced Expression of <i>miR-181b</i> in B Cells of CLL Improves the Anti-Tumor Cytotoxic T Cell Response

The clinical progression of B cell chronic lymphocytic leukemia (CLL) is associated with immune cell dysfunction and a strong decrease of <i>miR-181b-5p</i> (<i>miR-181b</i>), promoting the death of CLL cells. Here we investigated whether the reduction of <i>miR-181b<...

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Bibliographic Details
Main Authors: Mirco Di Marco, Serena Veschi, Paola Lanuti, Alice Ramassone, Stefania Pacillo, Sara Pagotto, Felice Pepe, Jonahunnatha Nesson George-William, Claudia Curcio, Marco Marchisio, Sebastiano Miscia, Idanna Innocenti, Francesco Autore, Barbara Vannata, Patrizia Di Gregorio, Mario Di Gioacchino, Silvia Valentinuzzi, Manuela Iezzi, Renato Mariani-Costantini, Luigi Maria Larocca, Luca Laurenti, Angelo Veronese, Rosa Visone
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
CLL
microRNA
<i>miR-181b</i>
cytotoxic T cells
CD40-CD40L
Online Access:https://www.mdpi.com/2072-6694/13/2/257

Internet

https://www.mdpi.com/2072-6694/13/2/257

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