Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition

Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition

Overexpression of the MYC oncogene is a key feature of many human malignancies including Burkitt lymphoma. While MYC is widely regarded to be a promising therapeutic target, a clinically effective MYC inhibitor is still elusive. Here, we report an alternative strategy, targeting MYC indirectly throu...

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Bibliographic Details
Main Authors: Candace J. Poole, Wenli Zheng, Haesung Lee, Danielle Young, Atul Lodh, Ahmed Chadli, Jan van Riggelen
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cancers
Subjects:
MYC
HSP90
17-DMAG
17-AAG
Burkitt lymphoma
Online Access:https://www.mdpi.com/2072-6694/10/11/448

Internet

https://www.mdpi.com/2072-6694/10/11/448

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