No difference in the rate of change in telomere length or telomerase activity in HIV-infected patients after three years of darunavir/ritonavir with and without nucleoside analogues in the MONET trial.

No difference in the rate of change in telomere length or telomerase activity in HIV-infected patients after three years of darunavir/ritonavir with and without nucleoside analogues in the MONET trial.

To determine whether nucleos(t)ide reverse transcriptase inhibitors (NRTI) contribute to an accelerated loss in telomere length (TL) in HIV-infected patients on antiretroviral therapy (ART).Substudy of randomised controlled trial.Patients with HIV RNA <50 copies/mL on combination ART (n = 256) we...

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Bibliographic Details
Main Authors: Ajantha Solomon, Surekha Tennakoon, Edwin Leeansyah, Jose Arribas, Andrew Hill, Yvon Van Delft, Christiane Moecklinghoff, Sharon R Lewin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219673?pdf=render

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http://europepmc.org/articles/PMC4219673?pdf=render

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