Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation
Abstract Background Azithromycin, an antibiotic used for multiple infectious disorders, exhibits anti-inflammatory effects, but the molecular basis for this activity is not well characterized. Azithromycin inhibits IL-1β-mediated inflammation that is dependent, in part, on inflammasome activity. Her...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-06-01
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| Series: | Respiratory Research |
| Online Access: | http://link.springer.com/article/10.1186/s12931-017-0608-8 |