HTLV-1 Alters T Cells for Viral Persistence and Transmission

Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory diseases. Two viral factors, Tax and HTLV-1 bZIP factor (HBZ), are thought to be involved in the leukemogenesis of ATL. Tax expr...

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Bibliographic Details
Main Authors: Azusa Tanaka, Masao Matsuoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
HBZ
tax
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00461/full