Radical Roles for RAGE in the Pathogenesis of Oxidative Stress in Cardiovascular Diseases and Beyond

Radical Roles for RAGE in the Pathogenesis of Oxidative Stress in Cardiovascular Diseases and Beyond

Oxidative stress is a central mechanism by which the receptor for advanced glycation endproducts (RAGE) mediates its pathological effects. Multiple experimental inquiries in RAGE-expressing cultured cells have demonstrated that ligand-RAGE interaction mediates generation of reactive oxygen species (...

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Bibliographic Details
Main Authors: Radha Ananthakrishnan, Ravichandran Ramasamy, Karen M. O'Shea, Carmen Hurtado del Pozo, Gurdip Daffu, Ann Marie Schmidt
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:International Journal of Molecular Sciences
Subjects:
receptor for advanced glycation endproduct
non-enzymatic glycation
inflammation
redox signaling
Online Access:http://www.mdpi.com/1422-0067/14/10/19891

Internet

http://www.mdpi.com/1422-0067/14/10/19891

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