Physiologic and molecular consequences of endothelial Bmpr2 mutation

Physiologic and molecular consequences of endothelial Bmpr2 mutation

<p>Abstract</p> <p>Background</p> <p>Pulmonary arterial hypertension (PAH) is thought to be driven by dysfunction of pulmonary vascular microendothelial cells (PMVEC). Most hereditary PAH is associated with BMPR2 mutations. However, the physiologic and molecular consequ...

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Bibliographic Details
Main Authors: Crona Daniel, Paradis Helene, Gendron Robert, Johnson Jennifer A, Harral Julie, Blackwell Thomas, Hagen Moira, Majka Susan, Loyd James E, Nozik-Grayck Eva, Stenmark Kurt R, West James
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Respiratory Research
Subjects:
Pulmonary Arterial Hypertension
mouse model
pulmonary vascular disease
Online Access:http://respiratory-research.com/content/12/1/84

Internet

http://respiratory-research.com/content/12/1/84

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