LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro

LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro

Abstract Background This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in vitro. Methods U-2 OS cell lines expressing GR isoforms, different cell l...

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Bibliographic Details
Main Authors: Maria Luisa Molina, Julia Guerrero, John A. Cidlowski, Héctor Gatica, Annelise Goecke
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Inflammation
Subjects:
Lipopolysaccharide
Glucocorticoid receptor
Glucocorticoid resistance
Acute inflammation
Online Access:http://link.springer.com/article/10.1186/s12950-017-0169-0

Internet

http://link.springer.com/article/10.1186/s12950-017-0169-0

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