Fabrication of Circular Obelisk-Type Multilayer Microneedles Using Micro-Milling and Spray Deposition

Fabrication of Circular Obelisk-Type Multilayer Microneedles Using Micro-Milling and Spray Deposition

In this study we present the fabrication of multilayer microneedles with circular obelisk and beveled-circular obelisk geometries, which have potential applications in implantable drug delivery devices. Micro-milling was adopted as an environmental-friendly and cost-effective way to fabricate primar...

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Bibliographic Details
Main Authors: Min Jung Kim, Seok Chan Park, Binod Rizal, Giselle Guanes, Seung-Ki Baek, Jung-Hwan Park, Amy R. Betz, Seong-O Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
polymer microneedle
transdermal drug delivery
spray deposition
micro-milling
obelisk
circular dichroism
Online Access:http://journal.frontiersin.org/article/10.3389/fbioe.2018.00054/full

Internet

http://journal.frontiersin.org/article/10.3389/fbioe.2018.00054/full

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