Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein.

Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein.

Malaria remains a major global public health problem with an estimated 200 million cases detected in 2012. Although the most advanced candidate malaria vaccine (RTS,S) has shown promise in clinical trials, its modest efficacy and durability have created uncertainty about the impact of RTS,S immuniza...

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Bibliographic Details
Main Authors: Marcela Parra, Xia Liu, Steven C Derrick, Amy Yang, Alvaro Molina-Cruz, Carolina Barillas-Mury, Hong Zheng, Phuong Thao Pham, Martha Sedegah, Arnel Belmonte, Dianne D Litilit, Thomas A Waldmann, Sanjai Kumar, Sheldon L Morris, Liyanage P Perera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4624717?pdf=render

Internet

http://europepmc.org/articles/PMC4624717?pdf=render

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