Cluster analysis on high dimensional RNA-seq data with applications to cancer research - An evaluation study.

BACKGROUND:Clustering of gene expression data is widely used to identify novel subtypes of cancer. Plenty of clustering approaches have been proposed, but there is a lack of knowledge regarding their relative merits and how data characteristics influence the performance. We evaluate how cluster anal...

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Bibliographic Details
Main Authors: Linda Vidman, David Källberg, Patrik Rydén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219102