Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs

Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs

Abstract Background Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation generates complex barcodes underlying diverse DVL3 fun...

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Bibliographic Details
Main Authors: Kateřina Hanáková, Ondřej Bernatík, Marek Kravec, Miroslav Micka, Jitender Kumar, Jakub Harnoš, Petra Ovesná, Petra Paclíková, Matěj Rádsetoulal, David Potěšil, Konstantinos Tripsianes, Lukáš Čajánek, Zbyněk Zdráhal, Vítězslav Bryja
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cell Communication and Signaling
Subjects:
Dishevelled
DVL3
Phosphorylation
Kinase
Mass spectrometry
CK1
Online Access:https://doi.org/10.1186/s12964-019-0470-z

Internet

https://doi.org/10.1186/s12964-019-0470-z

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