Closed-Loop Deep Brain Stimulation to Treat Medication-Refractory Freezing of Gait in Parkinson’s Disease

Closed-Loop Deep Brain Stimulation to Treat Medication-Refractory Freezing of Gait in Parkinson’s Disease

Background: Treating medication-refractory freezing of gait (FoG) in Parkinson’s disease (PD) remains challenging despite several trials reporting improvements in motor symptoms using subthalamic nucleus or globus pallidus internus (GPi) deep brain stimulation (DBS). Pedunculopontine nucleus (PPN) r...

Full description

Bibliographic Details
Main Authors: Rene Molina, Chris J. Hass, Stephanie Cernera, Kristen Sowalsky, Abigail C. Schmitt, Jaimie A. Roper, Daniel Martinez-Ramirez, Enrico Opri, Christopher W. Hess, Robert S. Eisinger, Kelly D. Foote, Aysegul Gunduz, Michael S. Okun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Human Neuroscience
Subjects:
freezing of gait (FOG)
Parkinson’s disease
pedunculopontine nucleus
closed-loop
deep brain stimulation
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2021.633655/full

Internet

https://www.frontiersin.org/articles/10.3389/fnhum.2021.633655/full

Similar Items