Generation of Infectious Mimivirus Virions Through Inoculation of Viral DNA Within Acanthamoeba castellanii Shows Involvement of Five Proteins, Essentially Uncharacterized

Generation of Infectious Mimivirus Virions Through Inoculation of Viral DNA Within Acanthamoeba castellanii Shows Involvement of Five Proteins, Essentially Uncharacterized

One of the most curious findings associated with the discovery of Acanthamoeba polyphaga mimivirus (APMV) was the presence of many proteins and RNAs within the virion. Although some hypotheses on their role in Acanthamoeba infection have been put forward, none have been validated. In this study, we...

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Bibliographic Details
Main Authors: Dehia Sahmi-Bounsiar, Jean-Pierre Baudoin, Sihem Hannat, Philippe Decloquement, Eric Chabrieres, Sarah Aherfi, Bernard La Scola
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Microbiology
Subjects:
L442
single-cell transfection
microinjection
Acanthamoeba castellanii
ApMV
L724
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.677847/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.677847/full

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