Anesthetic-Induced Oxidative Stress and Potential Protection

Prolonged exposure of developing mammals to general anesthetics affects the N-methyl-D-aspartate (NMDA)–type glutamate or γ-aminobutyric acid (GABA) receptor systems and enhances neuronal toxicity. Stimulation of immature neurons by NMDA antagonists or GABA agonists is thought to increase overall ne...

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Bibliographic Details
Main Authors: Cheng Wang, Xuan Zhang, Fang Liu, Merle G. Paule, William Slikker, Jr.
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2010.118