Therapeutic effect of two altered peptide ligands derived from the human heat shock protein 60 in experimental models of rheumatoid arthritis

Therapeutic effect of two altered peptide ligands derived from the human heat shock protein 60 in experimental models of rheumatoid arthritis

Induction of immune tolerance as therapeutic approach for autoimmune diseases constitutes a current research focal point. In this sense, two Altered Peptide Ligands (APLs) were evaluated for the induction of peripheral tolerance in patients with Rheumatoid Arthritis (RA). Two novel T cell epitopes f...

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Bibliographic Details
Main Authors: María del C Domínguez, Norailys Lorenzo, Ariana Barberá, Gabriel Padrón, Ana María Torres, María V Hernández, Isabel Hernández, Rafael Gil, Aniel Sánchez, Vladimir Besada, Luis J González, Hilda Garay, Osvaldo Reyes, Ever Pérez, Matilde López, Yuliet Mazola, Karelia Cosme, Julio Ancizar
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
rheumatoid arthritis
altered peptide ligand
hhsp60
immune tolerance
regulatory t cells
collagen induced arthritis
adjuvant induced arthritis
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522013000200011&lng=en&tlng=en

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http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522013000200011&lng=en&tlng=en

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