Investigating the effects of two novel 4-MMPB analogs as potent lipoxygenase inhibitors for prostate cancer treatment

Investigating the effects of two novel 4-MMPB analogs as potent lipoxygenase inhibitors for prostate cancer treatment

Abstract Background Lipoxygenases are one of the critical signaling mediators which can be targeted for human prostate cancer (PC) therapy. In this study, 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine (4-MMPB) and its two analogs, 4-propyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzoth...

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Bibliographic Details
Main Authors: Sonia Iranpour, Aseel Kamil Mohammed Al-Mosawi, Ahmad Reza Bahrami, Hamid Sadeghian, Maryam M. Matin
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Biological Research - Thessaloniki
Subjects:
Prostate cancer
Lipoxygenases
Chemotherapy
Targeted therapy
Online Access:https://doi.org/10.1186/s40709-021-00141-w

Internet

https://doi.org/10.1186/s40709-021-00141-w

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