Cisplatin-Induced Non-Oliguric Acute Kidney Injury in a Pediatric Experimental Animal Model in Piglets.

OBJECTIVE:To design an experimental pediatric animal model of acute kidney injury induced by cisplatin. METHODS:Prospective comparative observational animal study in two different phases. Acute kidney injury was induced using three different doses of cisplatin (2, 3 and 5 mg/kg). The development of...

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Bibliographic Details
Main Authors: Maria José Santiago, Sarah Nicole Fernández, Alberto Lázaro, Rafael González, Javier Urbano, Jorge López, Maria José Solana, Blanca Toledo, Jimena Del Castillo, Alberto Tejedor, Jesús López-Herce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752347?pdf=render