Next Generation Sequencing in MPNs. Lessons from the Past and Prospects for Use as Predictors of Prognosis and Treatment Responses

Next Generation Sequencing in MPNs. Lessons from the Past and Prospects for Use as Predictors of Prognosis and Treatment Responses

The myeloproliferative neoplasms (MPNs) are acquired hematological stem cell neoplasms characterized by driver mutations in <i>JAK2</i>, <i>CALR</i>, or <i>MPL</i>. Additive mutations may appear in predominantly epigenetic regulator, RNA splicing and signaling pat...

Full description

Bibliographic Details
Main Author: Vibe Skov
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
myeloproliferative neoplasms
essential thrombocythemia
polycythemia vera
myelofibrosis
next generation sequencing
gene mutations
Online Access:https://www.mdpi.com/2072-6694/12/8/2194

Internet

https://www.mdpi.com/2072-6694/12/8/2194

Similar Items