Levodopa Modulates Functional Connectivity in the Upper Beta Band Between Subthalamic Nucleus and Muscle Activity in Tonic and Phasic Motor Activity Patterns in Parkinson’s Disease

Levodopa Modulates Functional Connectivity in the Upper Beta Band Between Subthalamic Nucleus and Muscle Activity in Tonic and Phasic Motor Activity Patterns in Parkinson’s Disease

Introduction: Striatal dopamine depletion disrupts basal ganglia function and causes Parkinson’s disease (PD). The pathophysiology of the dopamine-dependent relationship between basal ganglia signaling and motor control, however, is not fully understood. We obtained simultaneous recordings of local...

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Bibliographic Details
Main Authors: Uri E. Ramirez Pasos, Frank Steigerwald, Martin M. Reich, Cordula Matthies, Jens Volkmann, René Reese
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Human Neuroscience
Subjects:
Parkinson’s disease
subthalamic nucleus
deep brain stimulation
local field potentials
dopamine
movement
Online Access:https://www.frontiersin.org/article/10.3389/fnhum.2019.00223/full

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https://www.frontiersin.org/article/10.3389/fnhum.2019.00223/full

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