Delayed Gut Colonization Shapes Future Allergic Responses in a Murine Model of Atopic Dermatitis

Delayed Gut Colonization Shapes Future Allergic Responses in a Murine Model of Atopic Dermatitis

Epidemiological studies have long reported that perturbations of the childhood microbiome increase the risk of developing allergies, but a causal relationship with atopic dermatitis remains unclear. Here we colonized germ-free mice at birth or at one or eight week-of-age to investigate the role of p...

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Bibliographic Details
Main Authors: Amalie W. Arildsen, Line F. Zachariassen, Lukasz Krych, Axel K. Hansen, Camilla H. F. Hansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
allergy
atopic dermatitis
childhood ezcema
early priming
gut microbiota
immune maturation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.650621/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.650621/full

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