S-nitrosoglutathione accelerates recovery from 5-fluorouracil-induced oral mucositis.

S-nitrosoglutathione accelerates recovery from 5-fluorouracil-induced oral mucositis.

<h4>Introduction</h4>Mucositis induced by anti-neoplastic drugs is an important, dose-limiting and costly side-effect of cancer therapy.<h4>Aim</h4>To evaluate the effect of the topical application of S-nitrosoglutathione (GSNO), a nitric oxide donor, on 5-fluorouracil (5-FU)...

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Bibliographic Details
Main Authors: Maria Adriana Skeff, Gerly A C Brito, Marcelo G de Oliveira, Cintia M Braga, Matheus M Cavalcante, Victor Baldim, Rosenilde C Holanda-Afonso, Carina M Silva-Boghossian, Ana Paula Colombo, Ronaldo A Ribeiro, Vivaldo Moura-Neto, Renata F C Leitão
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0113378

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https://doi.org/10.1371/journal.pone.0113378

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