Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

Abstract Mosaic loss of chromosome Y (LOY) in immune cells is a male-specific mutation associated with increased risk for morbidity and mortality. The CD99 gene, positioned in the pseudoautosomal regions of chromosomes X and Y, encodes a cell surface protein essential for several key properties of l...

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Bibliographic Details
Main Authors: Jonas Mattisson, Marcus Danielsson, Maria Hammond, Hanna Davies, Caroline J. Gallant, Jessica Nordlund, Amanda Raine, Malin Edén, Lena Kilander, Martin Ingelsson, Jan P. Dumanski, Jonatan Halvardson, Lars A. Forsberg
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94588-5

Internet

https://doi.org/10.1038/s41598-021-94588-5

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