Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse.

Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse.

Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical studies in mice, rats, and monkeys have repeatedly demonstrated that exposure to anesthetic agents during early post-natal periods can lead to acute neurotoxicity. More concerning, later-life defects in...

Full description

Bibliographic Details
Main Authors: Simon C Johnson, Amanda Pan, Grace X Sun, Arielle Freed, Julia C Stokes, Rebecca Bornstein, Michael Witkowski, Li Li, Jeremy M Ford, Christopher R A Howard, Margaret M Sedensky, Philip G Morgan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213543

Internet

https://doi.org/10.1371/journal.pone.0213543

Similar Items