progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement.

Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms.We describe a new method to align two or more genomes that have undergone rear...

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Bibliographic Details
Main Authors: Aaron E Darling, Bob Mau, Nicole T Perna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2892488?pdf=render