No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C(♦)(♦)This work was supported by a grant No. NR9412-3/2007 given by the Czech Ministry of Health.

No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C(♦)(♦)This work was supported by a grant No. NR9412-3/2007 given by the Czech Ministry of Health.

Background. Heme oxygenase-1 (HMOX1) and bilirubin UDP-glucuronosyltransferase (UGT1A1), both enzymes involved in bilirubin homeostasis, play an important role inoxidative stress defense.Objective. To assess the effect of promotervariations of HMOX1 and UGT1A1 genes on the progression of fibrosis in...

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Bibliographic Details
Main Authors: Petr Urbánek, Martin Leníček, Lucie Muchová, Iva Subhanová, Ladislav Dušek, Nikola Kaspříkova, Petr Hrabal, Radan Brůha, Libor Vítek
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Annals of Hepatology
Subjects:
Bilirubin
Heme oxygenase
Bilirubin UDP-glucuronosyltransferase
Oxidative stress
Genetic predisposition
Online Access:http://www.sciencedirect.com/science/article/pii/S166526811931511X

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http://www.sciencedirect.com/science/article/pii/S166526811931511X

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