Comprehensive Genomic Profiling Reveals Diverse but Actionable Molecular Portfolios across Hematologic Malignancies: Implications for Next Generation Clinical Trials

Comprehensive Genomic Profiling Reveals Diverse but Actionable Molecular Portfolios across Hematologic Malignancies: Implications for Next Generation Clinical Trials

Background: The translation of genomic discoveries to the clinic is the cornerstone of precision medicine. However, incorporating next generation sequencing (NGS) of hematologic malignancies into clinical management remains limited. Methods: We describe 235 patients who underwent integrated NGS prof...

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Bibliographic Details
Main Authors: Natalie Galanina, Rafael Bejar, Michael Choi, Aaron Goodman, Matthew Wieduwilt, Carolyn Mulroney, Lisa Kim, Huwate Yeerna, Pablo Tamayo, Jo-Anne Vergilio, Tariq I. Mughal, Vincent Miller, Catriona Jamieson, Razelle Kurzrock
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
next generation sequencing
lymphoid malignancies
myeloid malignancies
precision medicine
Online Access:http://www.mdpi.com/2072-6694/11/1/11

Internet

http://www.mdpi.com/2072-6694/11/1/11

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