Prenylflavonoid Isoxanthohumol Sensitizes MCF-7/ADR Cells to Doxorubicin Cytotoxicity via Acting as a Substrate of ABCB1

Isoxanthohumol is a unique prenylflavonoid with the highest content in beer. Isoxanthohumol has multiple bioactivities and has recently received considerable attention in the scientific community. Nonetheless; its effect on drug resistant cancer cells has rarely been studied. In this paper; we inves...

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Bibliographic Details
Main Authors: Ming Liu, Weiyi Zhang, Wei Zhang, Xin Zhou, Ming Li, Jinlai Miao
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/9/7/208