The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis.

The human respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants, possibly due to the properties of the immature neonatal pulmonary immune system. Using the newborn lamb, a classical model of human lung development and a translational model of RSV...

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Bibliographic Details
Main Authors: Thomas Démoulins, Melanie Brügger, Beatrice Zumkehr, Blandina I Oliveira Esteves, Kemal Mehinagic, Amal Fahmi, Loïc Borcard, Adriano Taddeo, Damian Jandrasits, Horst Posthaus, Charaf Benarafa, Nicolas Ruggli, Marco P Alves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009529