Gene duplications contribute to the overrepresentation of interactions between proteins of a similar age

Gene duplications contribute to the overrepresentation of interactions between proteins of a similar age

<p>Abstract</p> <p>Background</p> <p>The study of biological networks and how they have evolved is fundamental to our understanding of the cell. By investigating how proteins of different ages are connected in the protein interaction network, one can infer how that netw...

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Bibliographic Details
Main Authors: Fokkens Like, Hogeweg Paulien, Snel Berend
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Evolutionary Biology
Subjects:
Network evolution
Protein age
Duplication
Subfunctionalization
Paralogs
Protein-protein interactions
Network growth model
Online Access:http://www.biomedcentral.com/1471-2148/12/99

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http://www.biomedcentral.com/1471-2148/12/99

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