A method for histopathological study of the multifocal nature of spinal cord lesions in murine experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is a well-established mouse model for multiple sclerosis and is characterized by infiltration of mononuclear cells and demyelination within the central nervous system along with the clinical symptoms of paralysis. EAE is a multifocal and random disease...

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Bibliographic Details
Main Authors: Katherine N. Gibson-Corley, Alexander W. Boyden, Mariah R. Leidinger, Allyn M. Lambertz, Georgina Ofori-Amanfo, Paul W. Naumann, J. Adam Goeken, Nitin J. Karandikar
Format: Article
Language:English
Published: PeerJ Inc. 2016-01-01
Series:PeerJ
Subjects:
EAE
Online Access:https://peerj.com/articles/1600.pdf