Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form

Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the biological and toxicological effects of an AhR lacking the entire PASB structurally diverse chemicals, including halogenated aromatic hydrocarbons. Ligand-dependent transformation of the AhR into its DNA...

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Bibliographic Details
Main Authors: Anatoly A. Soshilov, Stefano Motta, Laura Bonati, Michael S. Denison
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
aryl hydrocarbon receptor
AhR
heat shock protein 90
hsp90
2,3,7,8-tetrachlorodibenzo-p-dioxin
TCDD
Online Access:https://www.mdpi.com/1422-0067/21/7/2474

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https://www.mdpi.com/1422-0067/21/7/2474

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