Gene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector.

Gene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector.

Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite, Trypanosoma cruzi, and is transmitted by triatomine insects during its blood meal. Proliferative epimastigotes forms thrive inside the insects in the presence of heme (...

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Bibliographic Details
Main Authors: Marcia C Paes, Francis M S Saraiva, Natália P Nogueira, Carolina S D Vieira, Felipe A Dias, Ana Rossini, Vitor Lima Coelho, Attilio Pane, Fei Sang, Marcos Alcocer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007945

Internet

https://doi.org/10.1371/journal.pntd.0007945

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