Mmf1p Couples Amino Acid Metabolism to Mitochondrial DNA Maintenance in Saccharomyces cerevisiae
A variety of metabolic deficiencies and human diseases arise from the disruption of mitochondrial enzymes and/or loss of mitochondrial DNA. Mounting evidence shows that eukaryotes have conserved enzymes that prevent the accumulation of reactive metabolites that cause stress inside the mitochondrion....
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-02-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/9/1/e00084-18 |