Losartan Treatment Could Improve the Outcome of TBI Mice

Losartan Treatment Could Improve the Outcome of TBI Mice

Traumatic brain injury frequently leads to serious mortality and physical disability, yet effective treatments remains insufficient. TBI always leads to a series of secondary brain injuries including neuronal apoptosis, continuous inflammation, endoplasmic reticulum stress, and disruption of the blo...

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Bibliographic Details
Main Authors: Jianhua Xiong, Yalong Gao, Xiaotian Li, Kai Li, Qifeng Li, Jun Shen, Zhenying Han, Jianning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neurology
Subjects:
traumatic brain injury
blood brain barrier
endoplasmic reticulum stress
neuroinflammation
angiotensin II type 1 receptors blockage
tight junction proteins
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00992/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00992/full

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