Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Abstract Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide. Exogenous surfactant therapy, even for resea...

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Bibliographic Details
Main Authors: Ann M. Czyzewski, Lynda M. McCaig, Michelle T. Dohm, Lauren A. Broering, Li-Juan Yao, Nathan J. Brown, Maruti K. Didwania, Jennifer S. Lin, Jim F. Lewis, Ruud Veldhuizen, Annelise E. Barron
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25009-3

Internet

https://doi.org/10.1038/s41598-018-25009-3

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