Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

Adult stem cells are the ultimate source for replenishment of salivary gland (SG) tissue. Self-renewal ability of stem cells is dependent on extrinsic niche signals that have not been unraveled for the SG. The ductal compartment in SG has been identified as the location harboring stem cells. Here, w...

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Bibliographic Details
Main Authors: Martti Maimets, Cecilia Rocchi, Reinier Bron, Sarah Pringle, Jeroen Kuipers, Ben N.G. Giepmans, Robert G.J. Vries, Hans Clevers, Gerald de Haan, Ronald van Os, Robert P. Coppes
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003458