Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin
Epidermal knockout of integrin β1 results in complete disorganization of the basement membrane (BM), resulting in neonatal lethality. Here, we report that this disorganization is exacerbated by an early embryonic inflammatory response involving the recruitment of tissue-resident and monocyte-derived...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716311433 |