Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin

Epidermal knockout of integrin β1 results in complete disorganization of the basement membrane (BM), resulting in neonatal lethality. Here, we report that this disorganization is exacerbated by an early embryonic inflammatory response involving the recruitment of tissue-resident and monocyte-derived...

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Bibliographic Details
Main Authors: Ambika S. Kurbet, Samarth Hegde, Oindrila Bhattacharjee, Srujan Marepally, Praveen K. Vemula, Srikala Raghavan
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716311433