Binding of Cationic Bis-porphyrins Linked with p- or m-Xylylenediamine and Their Zinc(II) Complexes to Duplex DNA

Binding of Cationic Bis-porphyrins Linked with p- or m-Xylylenediamine and Their Zinc(II) Complexes to Duplex DNA

Spectroscopic, viscometric, and molecular docking analysis of binding of cationic bis-porphyrins linked with p- or m-xylylenediamine (H2pXy and H2mXy) and their zinc(II) complexes (ZnpXy and ZnmXy) to duplex DNA are described. H2pXy and H2mXy bound to calf thymus DNA (CTDNA) stronger than unichromop...

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Bibliographic Details
Main Authors: Tadayuki Uno, Naoki Yamakawa, Yoshinobu Ishikawa
Format: Article
Language:English
Published: MDPI AG 2008-12-01
Series:Molecules
Subjects:
Porphyrin
DNA
Binding mode
Zinc
Titration
Circular dichroism
Viscometry
Distamycin
Molecular docking simulation
Online Access:http://www.mdpi.com/1420-3049/13/12/3117/

Internet

http://www.mdpi.com/1420-3049/13/12/3117/

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