Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling
Abstract Background Meningiomas are the most common primary intracranial tumors in adults. While a majority of meningiomas are slow growing neoplasms that may cured by surgical resection, a subset demonstrates more aggressive behavior and insidiously recurs despite surgery and radiation, without eff...
Main Authors: | Yu Mei, Ziming Du, Changchen Hu, Noah F. Greenwald, Malak Abedalthagafi, Nathalie Y.R. Agar, Gavin P. Dunn, Wenya Linda Bi, Sandro Santagata, Ian F. Dunn |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-09-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-017-0189-7 |
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