An analysis of mutational signatures of synonymous mutations across 15 cancer types

Abstract Background Synonymous mutations have been identified to play important roles in cancer development, although they do not modify the protein sequences. However, relatively little research has specifically delineated the functionality of synonymous mutations in cancer. Results We investigated...

Full description

Bibliographic Details
Main Authors: Yannan Bin, Xiaojuan Wang, Le Zhao, Pengbo Wen, Junfeng Xia
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medical Genetics
Subjects:
Online Access:https://doi.org/10.1186/s12881-019-0926-4