Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway

More effective strategies are needed to prevent prostate cancer metastasis. Here they report CBP/p300-interacting transactivator with E/D-rich carboxy-terminal domain-2 (CITED2) to interact with nucleolin, p300, and PRMT5 subunits, and reveal a role of CITED2-nucleolin axis in prostate cancer metast...

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Bibliographic Details
Main Authors: Seung-Hyun Shin, Ga Young Lee, Mingyu Lee, Jengmin Kang, Hyun-Woo Shin, Yang-Sook Chun, Jong-Wan Park
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06606-2