Mutational analysis of androgen receptor gene in two families with androgen insensitivity

Mutational analysis of androgen receptor gene in two families with androgen insensitivity

Background: Androgen insensitivity syndrome (AIS) is a rare X-linked disorder due to mutations in the androgen receptor (AR) gene causing end-organ resistance to the androgenic hormone. Subjects and Methods: Genetic studies were carried out in two families by karyotype and targeted exome sequencing...

Full description

Bibliographic Details
Main Author: Radha Ramadevi Akella
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Androgen insensitivity syndrome
androgen receptor gene
mutation
X-linked recessive disorder
XY karyotype
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=4;spage=520;epage=523;aulast=Akella

Internet

http://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=4;spage=520;epage=523;aulast=Akella

Similar Items