Mechanism and consequence of abnormal calcium homeostasis in Rett syndrome astrocytes

Astrocytes play an important role in Rett syndrome (RTT) disease progression. Although the non-cell-autonomous effect of RTT astrocytes on neurons was documented, cell-autonomous phenotypes and mechanisms within RTT astrocytes are not well understood. We report that spontaneous calcium activity is a...

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Bibliographic Details
Main Authors: Qiping Dong, Qing Liu, Ronghui Li, Anxin Wang, Qian Bu, Kuan Hong Wang, Qiang Chang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33417