A translation-independent function of PheRS activates growth and proliferation in Drosophila

Aminoacyl transfer RNA (tRNA) synthetases (aaRSs) not only load the appropriate amino acid onto their cognate tRNAs, but many of them also perform additional functions that are not necessarily related to their canonical activities. Phenylalanyl tRNA synthetase (PheRS/FARS) levels are elevated in mul...

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Bibliographic Details
Main Authors: Manh Tin Ho, Jiongming Lu, Dominique Brunßen, Beat Suter
Format: Article
Language:English
Published: The Company of Biologists 2021-03-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/14/3/dmm048132