Functions of the nonsense-mediated mRNA decay pathway in Drosophila development.

Nonsense-mediated mRNA decay (NMD) is a cellular surveillance mechanism that degrades transcripts containing premature translation termination codons, and it also influences expression of certain wild-type transcripts. Although the biochemical mechanisms of NMD have been studied intensively, its dev...

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Bibliographic Details
Main Authors: Mark M Metzstein, Mark A Krasnow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1756896?pdf=render