TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment

Abstract Adipocytes arising from mesenchymal stem cells (MSCs) requires MSC adipocyte commitment and differentiation of preadipocytes to mature adipocytes. Several signaling and some cytokines affect the adipogenesis of MSCs. This review focuses on the roles of TGF-β/SMAD signaling in adipocyte comm...

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Bibliographic Details
Main Authors: Sheng-Nan Li, Jia-Fa Wu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-020-1552-y